Clinical Interventions

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Model Inputs \(\rightarrow\) Clinical Interventions

Clinical interventions refer to actions taken during pregnancy or at the time of delivery that may change the course of a woman’s natural history. The use of interventions depends on the site of delivery, and can be preventive (i.e. used if available), or curative (i.e. used in response to recognizing a complication). Preventive interventions can reduce the risk of complication incidence, while curative interventions reduce the risk of mortality/morbidity from a complication. Facilities are able to treat different severity levels of complications depending on their EmOC status, and the efficacy of interventions can also differ by site status. In the model, the probabilities of intervention availability/use are ensured to be non-decreasing by improving delivery site (e.g. we assume that CEmOC will always be at least as good as BEmOC).

We model the availability and efficacy of each intervention. Availability represents the probability that the intervention is able to be delivered at a particular site, and efficacy represents the inherent maximum clinical effectiveness of the intervention. The actual ‘real-word’ effectiveness of interventions is then modelled, accounting for the site-specific quality of care.

We model elective c-section and also preventive interventions and curative interventions (in response to recognized complication):

GMatH (Global Maternal Health) Model - Last updated: 28 November 2022

zward@hsph.harvard.edu